C18-MS-II
MULTI-PURPOSE 1.8–15 µm C 16% USP L1 pH 2–10
- Standard first-choice C18
- Sharp peaks for basic compounds
- Scales from UHPLC to prep
1.8C18-MS-II · 3C18-MS-II · 5C18-MS-II
COSMOSIL (Nacalai Tesque)
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COSMOSIL (Nacalai Tesque) in Nepal
✓ Authorised distributor in Nepal
J.S.S. Life Science is the authorised distributor of COSMOSIL (Nacalai Tesque) in Nepal, so you get genuine products direct from the manufacturer, with local technical support. COSMOSIL HPLC columns from Nacalai Tesque, Japan, for pharma QC and research labs in Nepal: C18-MS-II, C18-AR-II, C18-PAQ and COSMOCORE core-shell columns, plus Cholester, PBr, PFP, πNAP, HILIC, sugar, protein, RNA, chiral and SFC speciality phases.
Also see: Analysis & Testing.
COSMOSIL catalogue
980 COSMOSIL HPLC columns, guard cartridges and packing materials, by catalogue number
Search the COSMOSIL range by catalogue number or column name, or browse by category. Open the COSMOSIL catalogue
COSMOSIL (Nacalai Tesque)
HPLC Columns
COSMOSIL C18 columns, from UHPLC to preparative scale.
PARTICLE SIZES 1.8, 3, 5 and 15 µm; 2.6 µm core-shell SILICA High-purity porous spherical silica, 120 Å COLUMN SIZES 1.0–28 mm I.D., analytical to prep QUALITY Inspection report with every column
C18-AR-II
ACID-STABLE 3, 5, 15 µm C 17% USP L1 pH 1.5–7.5
- Polymeric C18, strong acid resistance
- Peptides and acidic compounds
- Retains planar compounds longer
3C18-AR-II · 5C18-AR-II · 15C18-AR-II
COSMOSIL (Nacalai Tesque)
C18-PAQ
100% AQUEOUS 3, 5, 15 µm C 11% USP L1 pH 2–7.5
- Stable in 100% water mobile phase
- Retains polar compounds
- Organic acids, nucleosides
3C18-PAQ · 5C18-PAQ · 15C18-PAQ
COSMOSIL (Nacalai Tesque)
C18-EB
BASIC COMPOUNDS 3 µm C 14.5% USP L1 pH 2–10
- Designed for basic compounds
- Recommended for low-MW drugs
- 3 µm for fast, sharp analysis
3C18-EB
COSMOSIL (Nacalai Tesque)
C18-SS
HARSH CONDITIONS 3 µm USP L1 pH 1–12
- Excellent alkali resistance
- Widest pH range of the series
- For harsh method conditions
3C18-SS
COSMOSIL (Nacalai Tesque)
COSMOCORE 2.6C18
CORE-SHELL 2.6 µm 90 Å C 7% pH 2–7.5
- Sub-2 µm efficiency, lower pressure
- Faster runs on HPLC or UHPLC
- Also as Cholester and PBr
COSMOCORE 2.6C18 · 2.6Cholester · 2.6PBr
COSMOSIL (Nacalai Tesque)
Other reversed phase: CN-MS (L10), C22-AR-II, C8-MS (L7), C4-MS (L26) and PE-MS (L11), all 5 µm, 120 Å.
COSMOSIL (Nacalai Tesque)
Specialty Columns
COSMOSIL selectivity beyond C18: isomers, polar, sugars, proteins and chiral.
Preparative · up to 28 mm I.D. Analytical · 1.0–4.6 mm I.D. Guard · columns and cartridges
Cholester
SHAPE SELECTIVITY 1.8–5 µm C 20% USP L101
- Cholesterol-bonded phase
- Geometric isomers C18 cannot resolve
- Catechins, flavones, vitamins
1.8/3/5Cholester · COSMOCORE
COSMOSIL (Nacalai Tesque)
PBr
POLAR IN RP 1.8–5 µm C 8% pH 2–7.5
- Pentabromobenzyl phase
- Retains polar compounds in RP
- Nucleobases, amines, sugars
3PBr · 5PBr · COSMOCORE 2.6PBr
COSMOSIL (Nacalai Tesque)
PFP · πNAP · PYE · NPE
π-π & DIPOLE 2.5–5 µm pH 2–7.5
- Stronger π-π than phenyl
- Aromatic and positional isomers
- Sterols, tocopherols (PYE)
5PFP (L43) · 2.5/5πNAP · 5PYE · 5NPE
COSMOSIL (Nacalai Tesque)
HILIC
HYDROPHILIC 2.5, 5 µm 120–130 Å USP L104
- Triazole phase with anion exchange
- Retains what C18 cannot
- Amino acids, polar drugs
2.5HILIC · 5HILIC
COSMOSIL (Nacalai Tesque)
Sugar-D · NH2-MS
SACCHARIDES 5 µm USP L8 (NH2)
- Polyamine phase, high durability
- Mono- and oligosaccharides
- Sugar alcohols, syrups, honey
5Sugar-D · 5NH2-MS
COSMOSIL (Nacalai Tesque)
Protein-R · AR-300 · HIC
PROTEINS 5 µm 300 Å
- Wide-pore RP for proteins
- C18, C8, C4, phenyl AR-300
- HIC keeps enzyme activity
Protein-R · C18/C8/C4/Ph-AR-300 · HIC
COSMOSIL (Nacalai Tesque)
Diol-II Series
GEL FILTRATION 5 µm 120–1,000 Å USP L20
- Aqueous SEC for proteins
- MW 5,000 to 700,000
- Polysaccharides and polymers
Diol-120-II · Diol-300-II · Diol-1000-II
COSMOSIL (Nacalai Tesque)
RNA Series
mRNA & OLIGOS 5 µm 1,000–2,000 Å
- SEC and RP for nucleic acids
- For strands over 100 nt
- Scales to preparative
RNA-SEC-1000 · RNA-SEC-2000 · RNA-RP1
COSMOSIL (Nacalai Tesque)
CHiRAL · SFC Series
CHIRAL & SFC 3, 5 µm pH 2–9
- Immobilised amylose/cellulose
- A, B and C selectors
- SFC: PY, HP, Diol, πMAX
CHiRAL A/B/C · SFC PY/HP/Diol/πMAX
COSMOSIL (Nacalai Tesque)
Also from COSMOSIL: SL-II normal phase, Buckyprep fullerene and CNT columns, bulk packing, HPLC solvents and accessories.
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